Careers

At Elise Biopharma, we innovate to accelerate groundbreaking biologics and therapeutics, transforming scientific insights into life-changing treatments. We’re seeking passionate, skilled individuals to join our dynamic team.

Current Job Openings:

Senior Scientist, Upstream Process Development
Position Summary:

Senior Scientists at Elise Biopharma are highly motivated leaders who supervise multiple projects, mentor junior scientists, and significantly contribute to the strategic growth and operational success of the company. This role specifically focuses on the development and optimization of mammalian upstream processes.

*Bilingual strongly preferred (French)

Responsibilities:
  • Provide expert technical leadership for designing, planning, and executing experiments focused on mammalian cell culture, upstream bioprocess development, and optimization.
  • Supervise bioreactor setup, operation, troubleshooting, and routine maintenance.
  • Ensure consistency, reproducibility, and reliability of upstream processes.
  • Independently analyze and interpret experimental data; document and communicate findings effectively through comprehensive reports and scientific presentations.
  • Collaborate closely with global teams; international travel for project-related activities will be required.
  • Stay abreast of scientific literature, emerging technologies, and methodologies relevant to cell culture and bioprocessing.
  • Lead the assessment and integration of innovative technologies and methodologies, evaluating their potential impact on business and scientific outcomes.
  • Provide guidance, mentorship, and technical coaching to junior staff, promoting a high-performance team culture.
  • Assist management with resource allocation, project scheduling, and strategic planning.
  • Ensure strict adherence to laboratory safety guidelines, environmental regulations, and good manufacturing practices (GMP).
Qualifications:
  • Ph.D., Master’s, or Bachelor’s degree in biology, biochemistry, biomedical/biochemical engineering, or a related scientific field.
  • Ph.D. with ≥2 years, Master’s with ≥5 years, or Bachelor’s with ≥8 years of experience in mammalian upstream process development, scale-up, and GMP manufacturing.
  • Proven hands-on experience operating bioreactors, including bench-scale and pilot-scale systems.
  • Strong knowledge of mammalian cell lines (CHO DG44, CHOK1, HEK293, NS0, PerC6).
  • Expertise in media development, feed strategy optimization, and cell line productivity enhancement.
  • Solid experience with analytical techniques (cell counting, viability assays, metabolite profiling).
  • Experience in design-of-experiment (DOE) methodologies and statistical analysis software (JMP, Minitab, Design Expert).
  • Strong troubleshooting and problem-solving skills, capable of addressing complex upstream processing issues.
  • Effective communication, organizational skills, and ability to work collaboratively in cross-functional teams.
  • Proficiency with Microsoft Office (Excel, Word, PowerPoint).
  • Ability to multitask efficiently and prioritize effectively in a fast-paced environment.
  • Flexible, innovative, and results-driven with strong business acumen.

Senior Scientist, Downstream Process Development
Position Summary:

Senior Scientists at Elise Biopharma drive innovative research and development efforts in downstream processing, leading teams to optimize purification processes, improve product quality, and facilitate scale-up to manufacturing. They mentor junior team members and collaborate extensively with cross-functional teams to achieve company objectives.

*Bilingual strongly preferred (French)

Responsibilities:
  • Lead technical planning, design, and execution of experiments focused on downstream process development, including chromatography, filtration, and purification techniques.
  • Manage setup, operation, troubleshooting, and routine maintenance of AKTA chromatography systems and related equipment.
  • Ensure robust and reproducible downstream processes through detailed process monitoring and analysis.
  • Analyze complex data sets, document experimental results comprehensively, and communicate findings clearly through written reports and presentations.
  • Engage in global collaboration requiring international travel for technology transfer and project meetings.
  • Stay current with scientific advancements and integrate innovative downstream processing technologies into existing workflows.
  • Conduct evaluations of new technologies, assessing their potential impacts on operations and business objectives.
  • Provide mentorship, training, and supervision to junior staff, fostering their technical and professional development.
  • Assist in resource planning, budgeting, and project management to meet strategic goals and timelines.
  • Promote rigorous adherence to safety standards, laboratory practices, and GMP regulations.
Qualifications:
  • Ph.D., Master’s, or Bachelor’s degree in biochemistry, biochemical engineering, chemical engineering, or related discipline.
  • Ph.D. with ≥2 years, Master’s with ≥5 years, or Bachelor’s with ≥8 years of experience in downstream bioprocess development and GMP scale-up.
  • Demonstrated expertise in chromatography techniques (ion exchange, affinity, hydrophobic interaction, mixed-mode), filtration methods (TFF, viral clearance), and protein formulation.
  • Hands-on proficiency with AKTA purification systems and troubleshooting equipment.
  • Proficiency in protein analytical methods such as HPLC, SDS-PAGE, ELISA, and mass spectrometry.
  • Experience in design-of-experiment (DOE) and statistical analysis software (JMP, Minitab, Design Expert).
  • Strong analytical, organizational, and problem-solving skills.
  • Excellent written and verbal communication skills, with demonstrated capacity for scientific reporting and presentations.
  • Proven ability to manage multiple projects simultaneously in a dynamic environment.
  • Highly collaborative with excellent teamwork skills.
  • Client-focused, proactive, and driven by innovation and scientific excellence.
  • Proficiency with Microsoft Office applications (Word, Excel, PowerPoint).
Senior Analytical Scientist
Position Summary:

Senior Analytical Scientists at Elise Biopharma lead critical analytical development efforts to ensure the robustness, accuracy, and regulatory compliance of biologics development. They are pivotal in supporting research, development, and manufacturing through advanced analytical methodologies and validation processes.

*Bilingual strongly preferred (French)

Responsibilities:
  • Develop, validate, and execute complex analytical methodologies including chromatography, mass spectrometry, ELISA, and other bioanalytical assays.
  • Lead analytical support for biologics characterization, stability testing, and quality control.
  • Independently analyze, interpret, and report analytical results comprehensively and accurately.
  • Collaborate extensively with international teams; international travel for project-related activities required.
  • Maintain expertise on current analytical technologies and methods, evaluating and integrating new techniques into existing analytical platforms.
  • Provide technical mentoring and supervision to junior scientists, fostering their professional growth.
  • Actively participate in resource allocation, strategic planning, and timeline management for analytical development projects.
  • Ensure strict compliance with laboratory safety standards, regulatory guidelines, and GMP practices.

Qualifications:

  • Ph.D., Master’s, or Bachelor’s degree in analytical chemistry, biochemistry, pharmaceutical sciences, or a closely related discipline.
  • Ph.D. with ≥2 years, Master’s with ≥5 years, or Bachelor’s with ≥8 years of experience in analytical development for biologics.
  • Proven expertise in analytical method development and validation for biologics, including HPLC, LC-MS, ELISA, electrophoresis, and bioassays.
  • Experience with regulatory documentation and submissions (FDA, EMA).
  • Skilled in statistical and data analysis software (JMP, Minitab, Design Expert).
  • Excellent organizational, analytical, and communication skills.
  • Ability to manage multiple concurrent projects efficiently and effectively.
  • Proficient with Microsoft Office suite (Word, Excel, PowerPoint).
  • Demonstrated teamwork and collaboration skills, proactive attitude, and commitment to innovation.
  • Flexible, results-oriented, and able to manage changing priorities effectively.
Senior Fermentation Scientist
Position Summary:

Senior Fermentation Scientists at Elise Biopharma lead innovative microbial fermentation projects, optimizing processes for recombinant protein production. They drive development and scale-up activities, mentor junior scientists, and collaborate closely with global teams.

Bilingual strongly preferred (French)
Travel required (>10%)

Responsibilities:
  • Design, develop, and optimize microbial fermentation processes for recombinant proteins and other biologics.
  • Operate, maintain, and troubleshoot fermentation equipment to ensure consistent and reliable processes.
  • Execute experimental designs, thoroughly analyze complex datasets, document results, and communicate findings effectively through detailed reports and presentations.
  • Collaborate with international teams, requiring frequent travel for project coordination and technology transfer.
  • Stay current with scientific advancements, emerging fermentation technologies, and industry best practices.
  • Lead evaluations and implementation of novel fermentation methodologies, enhancing operational efficiency and effectiveness.
  • Provide mentorship, training, and supervision to junior team members, fostering their professional development and performance.
  • Contribute actively to strategic planning, resource management, and project timelines.
  • Ensure rigorous compliance with laboratory safety standards, GMP regulations, and environmental guidelines.
Qualifications:
  • Ph.D., Master’s, or Bachelor’s degree in biochemical engineering, microbiology, biotechnology, or related field.
  • Ph.D. with ≥2 years, Master’s with ≥5 years, or Bachelor’s with ≥8 years of hands-on experience in microbial fermentation development and scale-up.
  • Proven expertise operating bench-scale and pilot-scale fermenters, optimizing microbial fermentation conditions.
  • Strong understanding of microbial physiology, metabolism, and genetic manipulation relevant to fermentation processes.
  • Proficiency in statistical design-of-experiment (DOE) software (e.g., JMP, Minitab, Design Expert).
  • Familiarity with analytical methods relevant to fermentation (cell density, metabolite profiling, protein quantification).
  • Excellent analytical, organizational, and troubleshooting skills.
  • Strong written and oral communication skills, with demonstrated ability to prepare detailed technical reports and presentations.
  • Ability to manage multiple complex projects concurrently in a dynamic environment.
  • Proven leadership and collaborative capabilities within cross-functional teams.
  • Proficiency in Microsoft Office applications (Word, Excel, PowerPoint).
  • Flexibility and willingness to travel internationally.

Benefits:

  • Comprehensive health insurance (medical, dental, vision)
  • 401(k) with company matching
  • Generous PTO and paid holidays
  • Professional development and training opportunities
  • Wellness program and on-site fitness facilities
🇩🇪 Business Development Manager – DACH Region (German Preferred)

Position Summary:
We are seeking a dynamic and results-driven Business Development Manager to expand Elise Biopharma’s footprint across the DACH region (Germany, Austria, Switzerland). This role is ideal for candidates with a strong understanding of the European biotech ecosystem, particularly in microbial manufacturing, recombinant proteins, and CDMO partnerships. You will identify high-value prospects, drive early engagement, and help position Elise as the go-to CDMO partner in the region.

Location: Remote (Germany preferred)
Reports To: Director of Global Business Development
Language: German fluency strongly preferred

Responsibilities:

  • Identify, qualify, and close new business opportunities with biotech and pharmaceutical clients across the DACH region
  • Develop and execute territory-specific outreach strategies targeting therapeutic, diagnostic, and food biotech applications
  • Serve as the key commercial point of contact during early proposal development and technical qualification
  • Coordinate with internal technical and project management teams to scope client needs and timelines
  • Represent Elise at conferences and trade shows across Europe
  • Provide regional intelligence on funding trends, competitors, and new technology platforms
  • Maintain accurate sales forecasts and CRM records

Qualifications:

  • Bachelor’s or Master’s in life sciences, bioprocessing, or business; Ph.D. preferred but not required
  • 5+ years of experience in CDMO or biotech BD/sales roles
  • Deep understanding of microbial fermentation and recombinant protein technologies
  • Strong interpersonal and presentation skills
  • Proven track record of meeting or exceeding sales targets
  • Willingness to travel (30–40%)
  • Fluency in German and professional English required

Location: Remote or hybrid (Berlin, Munich, Basel, or Vienna ideal)
Benefits: Same benefits package as existing roles (health, PTO, development support, etc.)

🇹🇷 Process Development Associate – Microbial Systems (Turkish Preferred)

Position Summary:
The Process Development Associate will work alongside fermentation, downstream, and analytical teams to assist in designing and executing microbial process development projects. This hands-on role is perfect for early-career professionals with a background in E. coli fermentation and an interest in supporting international CDMO collaborations—particularly with Turkish or MENA-region biotech clients.

Location: On-site (Massachusetts preferred)
Reports To: Senior Fermentation Scientist
Language: Turkish fluency preferred for client communication

Responsibilities:

  • Support upstream (fermentation) and downstream (purification) process development for microbial biologics
  • Prepare media, buffers, and small-scale fermentation runs under supervision
  • Record and analyze process parameters: OD, pH, DO, feed rates, and temperature control
  • Conduct SDS-PAGE, Bradford, endotoxin, and HPLC assays under guidance
  • Prepare detailed lab reports, SOPs, and batch records
  • Communicate with international partners in Turkish when needed (email and occasional call support)
  • Assist with inventory tracking and sample management
  • Support GMP documentation during tech transfer activities

Qualifications:

  • Bachelor’s degree in Biotechnology, Microbiology, Biochemical Engineering, or related field
  • 0–2 years of industry experience; co-op or internship in CDMO or fermentation strongly preferred
  • Understanding of microbial growth, fermentation systems, and basic downstream techniques
  • Strong attention to detail and data integrity
  • Experience with lab software (e.g., JMP, Excel, GraphPad)
  • Fluency in Turkish highly preferred; English proficiency required
  • Enthusiastic, proactive, and team-oriented

Location: On-site (U.S.) with international collaboration
Benefits: Full employee benefits package (health, PTO, 401(k), mentorship program)

🇨🇦 Fermentation Scientist – Probiotics & Synbiotics (French Preferred)


Position Summary:

Elise Biopharma is seeking a Fermentation Scientist to support our expanding nutraceutical probiotic and synbiotic CDMO services. This role will focus on developing and scaling fermentation processes for Lactobacillus, Bifidobacterium, Bacillus, and next-generation anaerobes like Akkermansia and Faecalibacterium. The scientist will lead strain optimization and high-density culture development, ensuring consistency from bench to GMP scale.

  • Location: Montréal, Québec (on-site)
  • Reports To: Director of Microbial Development
  • Language: French fluency strongly preferred; English proficiency required

Responsibilities:

  • Develop and optimize fermentation protocols for probiotic and synbiotic strains (batch, fed-batch, and anaerobic systems).
  • Conduct scale-up studies from 1 L to 500 L bioreactors, ensuring reproducibility and strain viability.
  • Apply Process Analytical Technology (PAT) for monitoring metabolites, dissolved oxygen, and viability.
  • Collaborate with formulation and downstream teams on stabilization strategies (spray-drying, lyophilization, encapsulation).
  • Author technical reports, SOPs, and regulatory documentation to support GRAS and nutraceutical filings.
  • Mentor junior staff and collaborate with client R&D teams.

Qualifications:

  • M.Sc. or Ph.D. in Microbiology, Biotechnology, Biochemical Engineering, or related field.
  • 3+ years of fermentation experience (industrial or academic); probiotic-specific experience preferred.
  • Hands-on knowledge of anaerobic fermentation, bioreactor operation, and viability assays.
  • Strong communication skills in French; English proficiency required.

Benefits: Health, PTO, pension match, mentorship program, and professional development support.

🇨🇦 Analytical Development Scientist – Exosomes & Extracellular Vesicles (French Preferred)


Position Summary:
We are looking for an Analytical Development Scientist to join our Exosome & EV CDMO platform in Montréal. This scientist will design, execute, and validate assays for exosome characterization and potency—helping clients move cutting-edge nanocarrier therapeutics into clinical pipelines.

  • Location: Montréal, Québec (on-site)
  • Reports To: Head of Analytical Development
  • Language: French fluency strongly preferred; English proficiency required

Responsibilities:

  • Develop and validate analytical methods for exosomes/EVs, including NTA, DLS, flow cytometry, ELISA, and Western blotting of surface markers (CD63, CD81, CD9).
  • Support QC testing of exosome identity, purity, and potency across multiple cell sources (MSCs, iPSCs, HEK293).
  • Collaborate with upstream teams to correlate production parameters with EV quality.
  • Prepare regulatory-grade documentation to support IND/IMPD filings.
  • Interface with clients to present analytical findings and project updates.
  • Contribute to method transfer and scale-up readiness for GMP lots.

Qualifications:

  • M.Sc. or Ph.D. in Analytical Chemistry, Biochemistry, or Biotechnology.
  • 2–5 years of industry or academic experience with EVs, exosomes, or nanoparticle analysis.
  • Familiarity with regulatory expectations for advanced biologics.
  • Strong technical writing and data analysis skills.
  • French fluency preferred; English proficiency required.

Benefits: Health, PTO, pension match, conference travel support, and training on advanced EV analytics.

Elise Biopharma Career graphic of woman working with Bioreactor, Join Elise - Build the future, Apply Now.

🇺🇸 Fermentation Specialist – Animal Health CDMO (Veterinary Biologics & Probiotics)

Position Summary:
We’re hiring a Fermentation Specialist to join our Animal Health CDMO platform in San Diego. You will design, scale, and operate microbial fermentations for veterinary biologics, enzymes, and probiotic/spore products—translating lab insights into robust GMP-ready processes for field-ready animal health therapies.

Location: San Diego, California (on-site)
Reports To: Director, Upstream Process Development
Language: English required; Spanish a plus

Responsibilities
  • Develop, optimize, and scale microbial processes (2–10 L → 50–500 L → 1,000–2,000 L), including E. coli, Pichia, and Bacillus (spore and vegetative) for veterinary use.
  • Execute fed-batch/continuous runs with DO-stat/exponential feeding; model kLa/OUR, oxygen enrichment, foam control, and heat removal.
  • Implement DoE and PAT (off-gas, capacitance, Raman/inline pH/DO) to lock design spaces; maintain electronic batch records (eBR/MES).
  • Lead CIP/SIP, sterilization, inoculum/seed train, and contamination prevention; write/own SOPs and deviation/CAPA responses.
  • Drive sporulation control (enzymes off / probiotics on), spore hardening, and CFU/spec verification with QC.
  • Partner with Downstream/Analytical to correlate titer, purity, CFU, and activity with upstream levers; support tech transfer to GMP suites.
  • Generate regulatory-grade documentation aligned to USDA APHIS, FDA CVM, and VICH expectations.
Qualifications
  • B.S./M.S. in Chemical/Biochemical Engineering, Microbiology, or related field (Ph.D. a plus).
  • 3–7 years in fermentation/upstream PD; hands-on with Bacillus (spore or enzyme) strongly preferred.
  • Demonstrated scale-up (≥200 L), DoE/PAT familiarity, and strong aseptic/CIP/SIP discipline.
  • Comfort with eBR/MES, data integrity (ALCOA+), and cross-functional tech transfer.
  • Nice-to-have: experience with animal health matrices (feed/water), GRAS/EFSA dossiers, or pelleting survivability studies.
Benefits

Competitive salary, medical/dental/vision, 401(k) with match, PTO, professional development, conference support, and exposure to advanced animal-health fermentation (Bacillus probiotics, veterinary enzymes, and species-aware bioprocessing).

Elise Biopharma is an Equal Opportunity Employer. We welcome candidates from all backgrounds to apply.

🌍 Creative Biotech Content Writer Internship – Remote, Anywhere

Position Summary

Elise Biopharma is seeking a Creative Biotech Content Writer Intern to join our growing digital and scientific communications team. This internship is designed for students or early-career professionals with a passion for science and storytelling who want to learn how to translate cutting-edge biotechnology into engaging, accessible content. You will write, edit, and publish blogs, social media posts, and thought-leadership pieces that connect the worlds of biopharma, CDMOs, and synthetic biology to audiences worldwide.

Location: Remote (open worldwide)
Reports To: Director of Sales & Marketing
Language: English (native fluency preferred; additional languages a plus)

Responsibilities

  • Research, draft, and edit long-form blog posts on biopharma, CDMOs, microbial fermentation, and next-generation biologics.
  • Create short-form content for LinkedIn, Twitter, and newsletters that captures attention and drives engagement.
  • Support SEO optimization: meta descriptions, slugs, keyword planning, and headline testing.
  • Work closely with scientists and business development teams to translate technical topics into compelling stories.
  • Participate in content strategy meetings; pitch creative ideas for new series, campaigns, and multimedia formats.
  • Assist in editing and polishing marketing decks, whitepapers, and thought-leadership documents.
  • Contribute to building a recognizable, modern biotech brand voice.

Qualifications

  • Enrolled in or recently graduated from a degree program in Biotechnology, Biology, Biochemistry, Communications, English, or a related field.
  • Demonstrated writing skills (academic, blog, or creative portfolio required).
  • Interest in biotechnology, CDMOs, or life sciences—scientific literacy preferred but not required.
  • Ability to balance technical accuracy with creative flair.
  • Comfortable working independently in a remote, fast-paced, deadline-driven environment.
  • Bonus: experience with WordPress, SEO tools, or graphic design.

Why Join Elise Biopharma?
  • Innovative Environment: Work on cutting-edge technologies in biologics.
  • Career Development: Continuous professional growth and training opportunities.
  • Collaborative Culture: Be part of a dynamic team dedicated to scientific excellence.

Ready to make an impact? Apply now and become part of the Elise Biopharma journey. Email your CV or resume to info@elisebiopharma.com and our team will be in touch.